Technical Data
030798
b2-Microglobulin, pI 5.3 (b2M)
Description:
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

Applications:
Suitable for use in Western Blot, ELISA.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:1000~16000

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG1467CT12.3.1Ascites
SizeStorageShippingSourceHost
100ul-20CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
Purified His-tagged B2M protein (fragment).
Purity:
Ascites
Form
Supplied as a liquid, crude ascites with 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rennella, E., et al. J. Mol. Biol. 401(2):286-297(2010)
Debelouchina, G.T., et al. J. Am. Chem. Soc. 132(30):10414-10423(2010)
Mumtaz, A., et al. Saudi J Kidney Dis Transpl 21(4):701-706(2010)
Guo, H.C., et al. Nature 360(6402):364-366(1992)