Technical Data
030822
CABC1 (ADCK3, CABC1, Chaperone activity of bc1 complex-like, mitochondrial, aarF domain-containing protein kinase 3)
Description:
This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.

Applications:
Suitable for use in Western Blot, Immunofluorescence, ELISA.

Recommended Dilution:
ELISA: 1:1000
Western Blot: 1:100~250
Immunofluorescence: 1:10~50

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG1,k216CT7.5.1Affinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
CABC1 Mab is generated from mouse immunized with CABC1 recombinant protein.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Lagier-Tourenne, C., et al. Am. J. Hum. Genet. 82(3):661-672(2008)
Mollet, J., et al. Am. J. Hum. Genet. 82(3):623-630(2008)
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
Iiizumi, M., et al. Cancer Res. 62(5):1246-1250(2002)