Technical Data
030963
FGG (FGG, Fibrinogen gamma chain)
Description:
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Applications:
Suitable for use in Western Blot, ELISA.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:200~1600

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG1546CT11.4.3Ascites
SizeStorageShippingSourceHost
100ul-20CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
FGG Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human FGG.
Purity:
Ascites
Form
Supplied as a liquid, crude ascites with 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Bahadori, B., et al. Thromb. Res. 126(4):350-352(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Fujihara, N., et al. Thromb. Haemost. 104(2):213-223(2010)
Undas, A., et al. Thromb. Haemost. 104(2):415-417(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)