Technical Data
031295
TLE4, ID (TLE4, KIAA1261, Transducin-like enhancer protein 4)
Description:
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).

Applications:
Suitable for use in Western Blot, ELISA.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100~250

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgM384CT24.1.3.4Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
TLE4 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from the center region of human TLE4.
Purity:
Purified by ammonium sulfate precipitation.
Form
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Liu, Y., et al. PLoS Genet. 5 (11), E1000707 (2009)
Hancock, D.B., et al. PLoS Genet. 5 (8), E1000623 (2009)
Stolk, L., et al. Nat. Genet. (2009) In press
Dayyani, F., et al. Blood 111(8):4338-4347(2008)
Heimbucher, T., et al. Mol. Cell. Biol. 27(1):340-351(2007)