Technical Data
031450
5HT3E, ID (HTR3E, 5-hydroxytryptamine receptor 3E, Serotonin receptor 3E)
Description:
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. HTR3E encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.

Applications:
Suitable for use in Western Blot, Flow Cytometry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
5HT3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-162 amino acids from the Central region of human 5HT3E.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Walstab, J., et al. J. Biol. Chem. 285(35):26956-26965(2010)
Hammer, C., et al. Pharmacogenomics 11(7):943-950(2010)
Lennertz, L., et al. Eur Neuropsychopharmacol 20(6):414-420(2010)
Goecke, T.W., et al. Acta Obstet Gynecol Scand 89(1):7-14(2010)
Schuhmacher, A., et al. Pharmacogenet. Genomics 19(11):843-851(2009)