Technical Data
ADM, ID (ADM, AM, Adrenomedullin, Proadrenomedullin N-20 terminal peptide, ProAM N-terminal 20 peptide)
ADM, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes.

Suitable for use in Western Blot, Flow Cytometry and ELISA. Other applications have not been tested.

Recommended Dilutions:
Western Blot: 1:1000
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As Reported
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 69-96 in the central region of human ADM, UniProt Accession #P35318. Species Sequence Homology: bovine
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Recognizes human ADM.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Kim, S.M., et al. FEBS Lett. 584(1):213-218(2010). 2. Oie, E., et al. Basic Res. Cardiol. 105(1):89-98(2010). 3. Nomura, I., et al. Regul. Pept. 158 (1-3), 127-131 (2009)