Technical Data
031646
ADNP, CT (ADNP, ADNP1, KIAA0784, Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein)
Description:
Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq].

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
ADNP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 830-860 amino acids from the C-terminal region of human ADNP.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human, mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Braitch, M., et al. Neuroimmunomodulation 17(2):120-125(2010)
Mandel, S., et al. J. Biol. Chem. 282(47):34448-34456(2007)
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Kankova, K., et al. Diabetologia 50(5):990-999(2007)