Technical Data
031681-FITC
AFF2, ID (AFF2, FMR2, OX19, AF4/FMR2 family member 2, Fragile X E mental retardation syndrome protein, Fragile X mental retardation 2 protein, Protein Ox19) (FITC)
Description:
This gene encodes a putative transcriptional activator that is a member of the AF4FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.

Applications:
Suitable for use in Western Blot, FLISA

Recommended Dilution:
FLISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze FITC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
AFF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 885-912 amino acids from the Central region of human AFF2.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Bensaid, M., et al. Nucleic Acids Res. 37(4):1269-1279(2009)
Brylawski, B.P., et al. Exp. Mol. Pathol. 82(2):190-196(2007)
Sharma, D., et al. Genet. Epidemiol. 20(1):129-144(2001)
Hillman, M.A., et al. J. Hum. Genet. 46(5):251-259(2001)
Musumeci, S.A., et al. Clin Neurophysiol 111(9):1632-1636(2000)