Technical Data
031706
AGR3, CT (AGR3, BCMP11, Anterior gradient protein 3 homolog, Breast cancer membrane protein 11)
Description:
AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications not tested.

Recommended Dilution:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 119-147 in the C-terminal region of human AGR3, UniProt Accession #Q8TD06.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes human AGR3.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Persson, S., et al. Mol. Phylogenet. Evol. 36(3):734-740(2005) 2. Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004) 3. Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003) 4. Fletcher, G.C., et al. Br. J. Cancer 88(4):579-585(2003) 5. Adam, P.J., et al. J. Biol. Chem. 278(8):6482-6489(2003)