Technical Data
AGR3, CT (AGR3, BCMP11, Anterior gradient protein 3 homolog, Breast cancer membrane protein 11)
AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.

Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications not tested.

Recommended Dilution:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As reported
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 119-147 in the C-terminal region of human AGR3, UniProt Accession #Q8TD06.
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Recognizes human AGR3.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Persson, S., et al. Mol. Phylogenet. Evol. 36(3):734-740(2005) 2. Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004) 3. Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003) 4. Fletcher, G.C., et al. Br. J. Cancer 88(4):579-585(2003) 5. Adam, P.J., et al. J. Biol. Chem. 278(8):6482-6489(2003)