Technical Data
031834
AMFR, ID (AMFR, RNF45, E3 ubiquitin-protein ligase AMFR, Autocrine motility factor receptor, isoform 2, RING finger protein 45, gp78)
Description:
Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
AMFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 370-400 amino acids from the Central region of human AMFR.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Joshi, B., et al. J. Biol. Chem. 285(12):8830-8839(2010)
Bernardi, K.M., et al. Mol. Biol. Cell 21(1):140-151(2010)
Ballar, P., et al. Int. J. Biochem. Cell Biol. 42(1):167-173(2010)
Shmueli, A., et al. Biochem. Biophys. Res. Commun. 390(3):758-762(2009)
Ying, Z., et al. Hum. Mol. Genet. 18(22):4268-4281(2009)