Technical Data
031974
APLP2, CT (APLP2, APPL2, Amyloid-like protein 2, APPH, Amyloid protein homolog, CDEI box-binding protein)
Description:
APLP2 may play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
APLP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 592-621 amino acids from the C-terminal region of human APLP2.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human, mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Tuli, A., et al. J. Biol. Chem. 284(49):34296-34307(2009)
Kaden, D., et al. J. Cell. Sci. 122 (PT 3), 368-377 (2009) :
Tuli, A., et al. J. Immunol. 181(3):1978-1987(2008)
Tuli, A., et al. Immunogenetics 60(6):303-313(2008)