		Technical Data
032004	AQP1, CT (AQP1, CHIP28, Aquaporin-1, Aquaporin-CHIP, Urine water channel, Water channel protein for red blood cells and kidney proximal tubule)

Description:
Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

0.25mg/ml

Immunogen:

AQP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-269 amino acids from the C-terminal region of human AQP1.

Purity:

Purified by Protein A affinity chromatography.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Specificity:

Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

Chen, L.M., et al. Am. J. Physiol. Regul. Integr. Comp. Physiol. 299 (5), R1163-R1174 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Shankardas, J., et al. Mol. Vis. 16, 1538-1548 (2010) :
Halverson, G.R., et al. Immunohematology 26(1):22-26(2010)
Sui, H., et al. Nature 414(6866):872-878(2001)