Technical Data
032053
ARHGEF4, CT (ARHGEF4, KIAA1112, Rho guanine nucleotide exchange factor 4, APC-stimulated guanine nucleotide exchange factor 1)
Description:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
ARHGEF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 572-599 amino acids from the C-terminal region of human ARHGEF4.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Lyons, R., et al. Leuk. Res. 34(1):109-115(2010)
Kawasaki, Y., et al. J. Biol. Chem. 284(33):22436-22443(2009)
Itoh, R.E., et al. J. Cell. Sci. 121 (PT 16), 2635-2642 (2008) :
Kurzik-Dumke, U., et al. Cell. Signal. 19(9):1973-1985(2007)
Kuraguchi, M., et al. PLoS Genet. 2 (9), E146 (2006) :