Technical Data
032487
Beclin1, BH3 Domain (BECN1, GT197, Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197)
Description:
Beclin1-BH3 plays a central role in autophagy (By similarity). It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications have not been tested.

Recommended Dilution:
Western Blot: 1:1000
Immunohistochemistry: 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 95-132 of human Beclin1-BH3, UniProt Accession #Q14457. Species sequence homology: bovine, chicken, porcine, rat, xenopus
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes human Beclin1-BH3. Species crossreactivity: mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Won,K.Y., et.al., Hum. Pathol. 41 (1), 107-112 (2010) Oberstein,A., et.al., J. Biol. Chem. 282 (17), 13123-13132 (2007)