Technical Data
033186
CAPNS2, ID (CAPNS2, Calpain small subunit 2, Calcium-dependent protease small subunit 2)
Description:
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.

Applications:
Suitable for use in Western Blot. Other applications have not been tested.

Recommended Dilution:
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide corresponding to aa55-83 from the central region of human CAPNS2, conjugated to KLH (Q96L46, NP_115706)
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes human CAPNS2. Species crossreactivity: mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 2. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) 3. Lamesch, P., et al. Genomics 89(3):307-315(2007) 4. Ma, H., et al. Curr. Eye Res. 29 (4-5), 337-347 (2004) : 5. Schad, E., et al. Biochem. J. 362 (PT 2), 383-388 (2002) :