Technical Data
033192-AP
CARM1, ID (CARM1, PRMT4, Histone-arginine methyltransferase CARM1, Coactivator-associated arginine methyltransferase 1, Protein arginine N-methyltransferase 4) (AP)
Description:
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al., 2002 [PubMed 11724789]).

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul4°C Do Not FreezeBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
CARM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the Central region of human CARM1.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phophatase (AP).
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Gao, X., et al. J. Cell. Biochem. 110(1):162-170(2010)
Carascossa, S., et al. Genes Dev. 24(7):708-719(2010)
Kim, Y.R., et al. BMC Cancer 10, 197 (2010) :
Ito, T., et al. BMC Dev. Biol. 9, 47 (2009) :
Haiman, C.A., et al. BMC Cancer 9, 43 (2009) :