Technical Data
033620
CDH11, CT (Cadherin-11, Osteoblast cadherin, OB-cadherin, OSF-4, CDH11, OB, CAD11, CDHOB)
Description:
CDH11 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Applications:
Suitable for use in Immunohistochemistry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Immunohistochemistry: 1:10-50

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
CDH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629~658 amino acids from the C-terminal region of human CDH11.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Chu,K., Mol. Cancer Res. 6 (8), 1259-1267 (2008)
Tamura,D., Int. J. Oncol. 33 (1), 17-24 (2008)
Getsios,S., Dev. Dyn. 211 (3), 238-247 (1998)