Technical Data
033629
CDH22, ID (CDH22, C20orf25, Cadherin-22, Pituitary and brain cadherin)
Description:
This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs.

Applications:
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested.

Recommended Dilutions:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 411-440 in the central region of human CDH22, UniProt Accession #Q9UJ99.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes human CDH22.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Lewis, J.P., et al. Genomics (2010) In press 2. Liu, Y., et al. Cancer Biol. Ther. 8(14):1352-1359(2009) 3. Zhou, J., et al. Tumour Biol. 30(3):130-140(2009) 4. Bento, J.L., et al. Genomics 92(4):226-234(2008) 5. Wu, J., et al. J. Endocrinol. 176(3):381-391(2003)