Technical Data
CDKN3, CT (CDKN3, CDI1, CIP2, KAP, Cyclin-dependent kinase inhibitor 3, CDK2-associated dual-specificity phosphatase, Cyclin-dependent kinase interactor 1, Cyclin-dependent kinase-interacting protein 2, Kinase-associated phosphatase)
CDKN3 belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. The gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers.

Suitable for use in Western Blot, Immunohistochemistry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As reported
CDKN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183~212 amino acids from the C-terminal region of human CDKN3.
Purified by Protein G affinity chromatography.
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Yeh, C.T., et al., Biochem. Biophys. Res. Commun. 305(2):311-314 (2003).
Yeh, C.T., et al., Cancer Res. 60(17):4697-4700 (2000).
Lee, S.W., et al., Mol. Cell. Biol. 20(5):1723-1732 (2000).
Poon, R.Y., et al., Science 270(5233):90-93 (1995).
Hannon, G.J., et al., Proc. Natl. Acad. Sci. U.S.A. 91(5):1731-1735 (1994).