Technical Data
033932
CLC, CT (CLC, Eosinophil lysophospholipase, Charcot-Leyden crystal protein, Galectin-10, Lysolecithin acylhydrolase)
Description:
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
CLC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-124 amino acids from the C-terminal region of human CLC.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Bryborn, M., et al. Allergy 65(2):220-228(2010)
De Re, V., et al. Ann. N. Y. Acad. Sci. 1173, 357-364 (2009) :
Than, N.G., et al. Proc. Natl. Acad. Sci. U.S.A. 106(24):9731-9736(2009)
Kubach, J., et al. Blood 110(5):1550-1558(2007)