Technical Data
CLDN2, CT (Y195) (CLDN2, Claudin-2, SP82)
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.

Suitable for use in Western Blot, Immunohistochemistry and Flow Cytometry. Other applications have not been tested.

Recommended Dilution:
Western Blot: 1:1000
Immunohistochemistry: 1:10-1:50
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As reported
Synthetic peptide corresponding to a portion of amino acids within aa174-201 from the C-terminal region of human CLDN2, conjugated with KLH.
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Recognizes human CLDN2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Smith, A.J., et al. J. Acquir. Immune Defic. Syndr. 55(3):306-315(2010) 2. Kojima, F., et al. Oncol. Rep. 23(4):927-931(2010) 3. Szakal, D.N., et al. Virchows Arch. 456(3):245-250(2010) 4. Buchert, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(6):2628-2633(2010) 5. Mankertz, J., et al. Cell Tissue Res. 336(1):67-77(2009)