Technical Data
033968
CLDN7, CT (CLDN7, CEPTRL2, CPETRL2, Claudin-7)
Description:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
CLDN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-209 amino acids from the C-terminal region of human CLDN7.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Kojima, F., et al. Oncol. Rep. 23(4):927-931(2010)
Rendon-Huerta, E., et al. J Gastrointest Cancer 41(1):52-59(2010)
Ouban, A., et al. Histol. Histopathol. 25(1):83-90(2010)
Kaarteenaho, R., et al. Respir. Res. 11, 59 (2010) :
Lal-Nag, M., et al. Genome Biol. 10 (8), 235 (2009) :