Technical Data
034095
COL4A6, ID (COL4A6, Collagen alpha-6(IV) chain)
Description:
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.

Applications:
Suitable for use in Western Blot. Other applications have not been tested.

Recommended Dilution:
Western Blot: 1:100-1:500
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide corresponding to a region between aa828-858 from the central region of human COL4A6, conjugated to KLH. Cellular Localization: secreted, extracellular space, extracellular matrix, basement membrane.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes human COL4A6.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Romero, R., et al. Am. J. Obstet. Gynecol. (2010) In press : 2. Bailey, S.D., et al. Diabetes Care (2010) In press : 3. Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) : 4. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) 5. Skovbjerg, H., et al. BMC Cancer 9, 136 (2009) :