Technical Data
COLQ, CT (COLQ, Acetylcholinesterase collagenic tail peptide, AChE Q subunit, Acetylcholinesterase-associated collagen)
This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As reported
COLQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human COLQ.
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Human, mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Mihaylova, V., et al. Brain 131 (PT 3), 747-759 (2008) :
Schreiner, F., et al. Neuromuscul. Disord. 17(3):262-265(2007)
Ting, A.K., et al. Chem. Biol. Interact. 157-158, 63-70 (2005) :
Dvir, H., et al. EMBO J. 23(22):4394-4405(2004)
Ishigaki, K., et al. Neuromuscul. Disord. 13(3):236-244(2003)