Technical Data
034130
CORO2A, ID (CORO2A, IR10, WDR2, Coronin-2A, WD repeat-containing protein 2)
Description:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
CORO2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-213 amino acids from the Central region of human CORO2A.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Jin, Y., et al. Nat. Genet. 42(7):576-578(2010)
Marshall, T.W., et al. J. Cell. Sci. 122 (PT 17), 3061-3069 (2009) :
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Yoon, H.G., et al. Mol. Cell 12(3):723-734(2003)
Yoon, H.G., et al. EMBO J. 22(6):1336-1346(2003)