Technical Data
034140
COX5B, ID (COX5B, Cytochrome c oxidase subunit 5B, mitochondrial, Cytochrome c oxidase polypeptide Vb)
Description:
Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain enzyme.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
COX5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the Central region of human COX5B.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Chen, Z.X., et al. Cell Death Differ. 17(3):408-420(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Beauchemin, A.M., et al. Brain Res. Bull. 56 (3-4), 285-297 (2001) :
Wu, H., et al. J. Biol. Chem. 275(42):32491-32498(2000)