Technical Data
COX7A1, ID (COX7A1, COX7AH, Cytochrome c oxidase subunit 7A1, mitochondrial, Cytochrome c oxidase subunit VIIa-heart, Cytochrome c oxidase subunit VIIa-muscle)
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are encoded by different genes.

Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceMouseRabbit
As reported
COX7A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the Central region of human COX7A1.
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Lazarou, M., et al. FEBS J. 276(22):6701-6713(2009)
Ronn, T., et al. Diabetologia 51(7):1159-1168(2008)
Grimwood, J., et al. Nature 428(6982):529-535(2004)