Technical Data
034298
CSRP3, ID (CSRP3, CLP, MLP, Cysteine and glycine-rich protein 3, Cardiac LIM protein, Cysteine-rich protein 3, LIM domain protein, cardiac, Muscle LIM protein)
Description:
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
CSRP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 amino acids from the Central region of human CSRP3.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)
Rampersaud, E., et al. Ann. Hum. Genet. 74(2):110-116(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Moller, D.V., et al. Eur. J. Heart Fail. 11(11):1031-1035(2009)