Technical Data
034334
CTNNA2, ID (CTNNA2, CAPR, Catenin alpha-2, Alpha N-catenin, Alpha-catenin-related protein)
Description:
The catenins (alpha, beta, and gamma) are cytoplasmic proteins found in varying abundance in many developing and adult tissues. Catenins bind directly or indirectly to the conserved cytoplasmic tail domain of the cell adhesion cadherins. The association of catenins to cadherins produces a complex, which is linked to the actin filament network. Catenins/cadherin complexes play an important role in mediating cell adhesion, transduction of cell-cell contact positional signals to the cell interior, and may play a crucial role in cell differentiation. Alpha-Catenin (CAP102, 102 kDa), originally described as an E-cadherin associated protein, has been shown to associate with other members of the cadherin family members, N-cadherin and P-cadherin.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanRabbit
Concentration:
0.25mg/ml
Immunogen:
CTNNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-190 amino acids from the Central region of human CTNNA2.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human, mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Scott, L.J., et al. Proc. Natl. Acad. Sci. U.S.A. 106(18):7501-7506(2009)
Lesch, K.P., et al. J Neural Transm 115(11):1573-1585(2008)
Mexal, S., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (6), 759-768 (2008)