Technical Data
034346
CTSD, CT (CTSD, CPSD, Cathepsin D, Cathepsin D light chain, Cathepsin D heavy chain)
Description:
CTSD encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-100

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
CTSD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383~412 amino acids from the C-terminal region of human CTSD.
Purity:
Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Christensen, B., et al. J. Biol. Chem. 285(11):7929-7937(2010)
Albayrak, O., et al. J. Gerontol. A Biol. Sci. Med. Sci. 65(3):219-224(2010)
Heinrich, M., et al. EMBO J. 18(19):5252-5263(1999)