Technical Data
034671
DLX4, ID (DLX4, BP1, DLX7, DLX8, DLX9, Homeobox protein DLX-4, Beta protein 1, Homeobox protein DLX-7, Homeobox protein DLX-8)
Description:
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
DLX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the Central region of human DLX4.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Schwartz, A.M., et al. Mod. Pathol. 22(1):1-6(2009)
Man, Y.G., et al. Cancer Biomark 5(1):9-17(2009)
Cavalli, L.R., et al. Cancer Genet. Cytogenet. 187(1):19-24(2008)
Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)