Technical Data
034853
DUSP13, CT (DUSP13, BEDP, MDSP, Dual specificity protein phosphatase 13 isoform MDSP, Branching-enzyme interacting DSP, Muscle-restricted DSP)
Description:
Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
DUSP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 146-173 amino acids selected from the C-terminal region of human DUSP13.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Kim, S.J., et al. Proteins 66(1):239-245(2007)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
Chen, H.H., et al. J. Biol. Chem. 279(40):41404-41413(2004)
Deloukas, P., et al. Nature 429(6990):375-381(2004)