Technical Data
034869
DVL2, CT (DVL2, Segment polarity protein dishevelled homolog DVL-2, DSH homolog 2)
Description:
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanRabbit
Concentration:
0.25mg/ml
Immunogen:
DVL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 587-617 amino acids from the C-terminal region of human DVL2.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Inkster, B., et al. Neuroimage 53(3):908-917(2010)
Kikuchi, K., et al. EMBO J. 29(20):3470-3483(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Gao, C., et al. Nat. Cell Biol. 12(8):781-790(2010)
Gnad, T., et al. Mol. Cancer 9, 31 (2010) :