Technical Data
034896
EBI3, CT (EBI3, IL27B, Interleukin-27 subunit beta, Epstein-Barr virus-induced gene 3 protein)
Description:
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanRabbit
Concentration:
0.25mg/ml
Immunogen:
EBI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the C-terminal region of human EBI3.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Kempe, S., et al. Am. J. Pathol. 175(1):440-447(2009)
Krumbiegel, D., et al. Pediatr Allergy Immunol 19(6):513-516(2008)
Poleganov, M.A., et al. Mol. Immunol. 45(10):2869-2880(2008)
Carl, J.W., et al. Int J Clin Exp Pathol 1(2):117-123(2008)
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)