Technical Data
035626
FGF7, ID (FGF7, KGF, Fibroblast growth factor 7, Heparin-binding growth factor 7, Keratinocyte growth factor)
Description:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

Applications:
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested.

Recommended Dilution:
Western Blot: 1:1000
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 57-86 in the central region of human FGF7, UniProt Accession #P21781. Species sequence homology: mouse, rat
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes human FGF7.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Lin, C.B., et al. J. Dermatol. Sci. 59(2):91-97(2010) Bando, M., et al. Immunol. Cell Biol. 88(3):328-333(2010) Wang, X., et al. Biomaterials 31(9):2542-2548(2010) Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) : Aguilar, S., et al. PLoS ONE 4 (11), E8013 (2009) :