Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
Suitable for use in Western Blot and ELISA. Other applications not tested.
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
| As Reported|
|KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 472-500 in the C-terminal region of human FZD5, UniProt Accession #NP_003459.2; Q13467.|
|Purified by Protein A affinity chromatography.|
|Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.|
|Recognizes human FZD5.|
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
1. Moller, M., et al. BMC Infect. Dis. 10, 154 (2010) 2. Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009) 3. Terabayashi, T., et al. J. Biol. Chem. 284(39):26716-26724 (2009) 4. Kim, J.G., et al. J. Korean Med. Sci. 24(3):443-447 (2009) 5. Lin, Z., et al. J. Biol. Chem. 283(48):33053-33058 (2008)|