Technical Data
HERV-FRD, NT (ERVFRD-1, ERVFRDE1, HERV-FRD_6p24.1 provirus ancestral Env polyprotein, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD, Syncytin-2, Surface protein, Transmembrane protein)
Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).

Suitable for use in Western Blot and ELISA. Other applications have not been tested.

Recommended Dilution:
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As reported
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 79-107 in the N-terminal region of human HERV-FRD, UniProt Accession #P60508. Species sequence homology: monkey
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Recognizes human HERV-FRD.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Vargas, A., et al. J. Mol. Biol. 392(2):301-318(2009) 2. Chen, C.P., et al. Biol. Reprod. 79(5):815-823(2008) 3. Malassine, A., et al. Retrovirology 5, 6 (2008) 4. Mangeney, M., et al. Proc. Natl. Acad. Sci. U.S.A. 104(51):20534-20539(2007) 5. Malassine, A., et al. Placenta 28 (2-3), 185-191 (2007) :