Technical Data
036702
HOXB6, ID (HOXB6, HOX2B, Homeobox protein Hox-B6, Homeobox protein Hox-2.2, Homeobox protein Hox-2B, Homeobox protein Hu-2)
Description:
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceMouseRabbit
Concentration:
As reported
Immunogen:
HOXB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-163 amino acids from the Central region of human HOXB6.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Ferrai, C., et al. Mol. Biol. Cell 20(15):3543-3551(2009)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Chen, T., et al. Eur. J. Hum. Genet. 15(1):23-28(2007)
Shen, W., et al. J. Biol. Chem. 279(38):39895-39904(2004)