Technical Data
IHH, NT (IHH, Indian hedgehog protein, HHG-2, Indian hedgehog protein N-product, Indian hedgehog protein C-product)
This gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.

Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested.

Recommended Dilutions:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As Reported
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 51-80 in the N-terminal region of human IHH, UniProt Accession #Q14623. Species Sequence Homology: mouse
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Recognizes human IHH.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Meulenbelt, I., et al. Ann. Rheum. Dis. (2010). 2. Kang, S.J., et al. Hum. Mol. Genet. 19(13):2725-2738(2010). 3. Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010). 4. Zhao, J., et al. BMC Med. Genet. 11, 96 (2010). 5. Chuang, P.T., et al. Nature 397(6720):617-621(1999)