Technical Data
037172
JAG1, CT (JAG1, JAGL1, Protein jagged-1, CD339)
Description:
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Applications:
Suitable for use in Western Blot, Flow Cytometry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
JAG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1129-1158 amino acids from the C-terminal region of human JAG1.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Foldi, J., et al. J. Immunol. 185(9):5023-5031(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kerns, D., et al. Schizophr. Res. 120 (1-3), 150-158 (2010) :
Siar, C.H., et al. Eur. J. Med. Res. 15(4):180-184(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :