Technical Data
037605
KRT16, ID (Keratin, type I cytoskeletal 16,KRT16,KRT16A)
Description:
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
KRT16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-167 amino acids from the Central region of human KRT16.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Leung, M.C., et al. J. Proteome Res. 9(10):5153-5163(2010)
Trost, A., et al. Mech. Ageing Dev. 131(5):346-353(2010)
Gruber, R., et al. Br. J. Dermatol. 161(6):1391-1395(2009)
Barcelos, A.C., et al. J. Cutan. Pathol. 36(6):647-654(2009)
Wu, C., et al. Exp. Dermatol. 17(8):645-652(2008)