Technical Data
MAP1ALC3, ID (T93/Y99) (LC3, APG8b, MAP1LC3B, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B,
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.

Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications have not been tested.

Recommended Dilution:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As reported
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 74-106 in the central region of human MAP1ALC3, UniProt Accession #NP_073729.1; Q9GZQ8; A6NCE7.
Purified by Protein A and peptide affinity chromatography.
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Recognizes human MAP1ALC3. Species crossreactivity: mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Rouschop, K.M., et al. J. Clin. Invest. 120(1):127-141(2010) Othman, E.Q., et al. J. Clin. Lab. Anal. 23(4):249-258(2009) Komatsu, M., et al. Cell 131(6):1149-1163(2007) Stelzl, U., et al. Cell 122(6):957-968(2005)Tanida, I., et al. J. Biol. Chem. 279(46):47704-47710(2004) He, H., et al. J. Biol. Chem. 278(31):29278-29287(2003) Tanida, I., et al. J. Biol. Chem. 277(16):13739-13744(2002) Tanida, I., et al. Biochem. Biophys. Res. Commun. 292(1):256-262(2002) Kabeya, Y., et al. EMBO J. 19(21):5720-5728(2000) Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)