Technical Data
MARCO, NT (MARCO, SCARA2, Macrophage receptor MARCO, Macrophage receptor with collagenous structure, Scavenger receptor class A member 2)
MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

Suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry. Other applications have not been tested.

Recommended Dilutions:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As Reported
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 13-40 in the N-terminal region of human MARCO, UniProt Accession #Q9UEW3.
Purified by Protein A affinity chromatography
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Recognizes human MARCO.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Wright, A.K., et al. J. Leukoc. Biol. 86(3):479-489 (2009). 2. Trynka, G., et al. Gut 58(8):1078-1083 (2009). 3. Arredouani, M.S., et al. J. Immunol. 175(9):6058-6064 (2005). 4. Liu, T., et al. J. Proteome Res. 4(6):2070-2080 (2005). 5. Seta, N., et al. Arthritis Rheum. 44(4):931-939(2001)