Technical Data
MID1, CT (MID1, FXY, RNF59, TRIM18, XPRF, Midline-1, Midin, Midline 1 RING finger protein, Putative transcription factor XPRF, RING finger protein 59, Tripartite motif-containing protein 18) (PE)
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing; however, the full-length nature of some of the variants has not been determined.

Suitable for use in Western Blot, FLISA

Recommended Dilution:
FLISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.
PabIgGAffinity Purified
200ul4C Do Not FreezeBlue IceHumanRabbit
As reported
MID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 574-603 amino acids from the C-terminal region of human MID1.
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Treutlein, J., et al. Arch. Gen. Psychiatry 66(7):773-784(2009)
Styrkarsdottir, U., et al. Nat. Genet. 41(1):15-17(2009)
Scapoli, L., et al. Eur. J. Oral Sci. 116(6):507-511(2008)
Aranda-Orgilles, B., et al. PLoS ONE 3 (10), E3507 (2008) :