Technical Data
038563-AP
MPO, CT (MPO, Myeloperoxidase, 89kD myeloperoxidase, 84kD myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain) (AP)
Description:
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq].

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Note: Applications are based on unconjugated antibody.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul4C Do Not FreezeBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
MPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 547-575 amino acids from the C-terminal region of human MPO.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Labeled with Alkaline Phosphatase.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Banerjee, M., et al. Toxicol. Appl. Pharmacol. 249(1):47-54(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Nahon, P., et al. Antioxid. Redox Signal. (2010) In press :
Wang, Y., et al. J. Huazhong Univ. Sci. Technol. Med. Sci. 30(4):437-442(2010)
Hua, F., et al. Zhongguo Fei Ai Za Zhi 13(2):122-127(2010)