Technical Data
039807
PDE6C, ID (PDE6C, PDEA2, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', cGMP phosphodiesterase 6C)
Description:
PDE6C is the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa.

Applications:
Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry (FFPE): 1:50-1:100
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As Reported
Immunogen:
KLH-conjugated synthetic peptide mapping to a fragment of residues within aa271-300 in central region of of human PDE6C, UniProt accession #P51160; Q91ZQ1.
Purity:
Purified by Protein A affinity chromatography followed by peptide affinity purification.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes human PDE6C. Species Crossreactivity: mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Muradov, H., et al. J. Biol. Chem. 284(47): 32662-32669 (2009). 2. Chang, B., et al. Proc. Natl. Acad. Sci. U.S.A. 106(46):19581-19586(2009). 3. Thiadens, A.A., et al. Am. J. Hum. Genet. 85(2):240-247 (2009)