Technical Data
039812
PDE8A, ID (Q348) (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A)
Description:
PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.

Applications:
Suitable for use in Immunohistochemistry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Immunohistochemistry: 1:10-50

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
PDE8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human PDE8A.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Wu,P., Proc. Natl. Acad. Sci. U.S.A. 101 (51), 17634-17639 (2004)
Gamanuma,M., Cell. Signal. 15 (6), 565-574 (2003)