Technical Data
042107-AP
SNX1, CT (SNX1, Sorting nexin-1) (AP)
Description:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Note: Applications are based on unconjugated antibody.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul4C Do Not FreezeBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
SNX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 425-455 amino acids from the C-terminal region of human SNX1.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Labeled with Alkaline Phosphatase.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Nisar, S., et al. Traffic 11(4):508-519(2010)
Mari, M., et al. Traffic 9(3):380-393(2008)
Bryant, D.M., et al. J. Cell. Sci. 120 (PT 10), 1818-1828 (2007) :
Rojas, R., et al. Mol. Cell. Biol. 27(3):1112-1124(2007)
Nguyen, L.N., et al. Clin. Cancer Res. 12(23):6952-6959(2006)