Technical Data
042535
SYT5, ID (SYT5, Synaptotagmin-5, Synaptotagmin V)
Description:
SYT5 may be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity).

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
SYT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-167 amino acids from the Central region of human SYT5.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Martins-de-Souza, D., et al. J Psychiatr Res (2010) In press :
Sreenath, A.S., et al. Clin. Biochem. 38(5):436-443(2005)
Mizutani, A., et al. J. Biol. Chem. 275(13):9823-9831(2000)
Craxton, M., et al. FEBS Lett. 460(3):417-422(1999)
Fukuda, M., et al. J. Biol. Chem. 274(44):31421-31427(1999)