Technical Data
042643
TBCA, ID (TBCA, Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A)
Description:
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceMouseRabbit
Concentration:
As reported
Immunogen:
TBCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human TBCA.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Bruneel, A., et al. Proteomics 5(15):3876-3884(2005)
Nolasco, S., et al. FEBS Lett. 579(17):3515-3524(2005)
Guasch, A., et al. J. Mol. Biol. 318(4):1139-1149(2002)